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Different classes of glutathione S-transferase. | Download Scientific Diagram https://i.ebayimg.com/images/g/SH0AAOSwm1RmZ6mD/s-l1200.jpg IV Solution Amount:1 Other inventorsSee patent ANTI-IL-1RAP CAR-T CELLS FOR THE TREATMENT OF ACUTE MYELOID LEUKEMIA Filed WO2025104669A1 See patent The disclosure provides methods of treating a refractory or relapsed acute myeloid leukemia (AML) in a subject comprising administration of a cell comprising a nucleic acid molecule encoding a chimeric antigen receptor (CAR), wherein the CAR comprises an antibody or antigen-binding fragment thereof that binds IL-1RAP, a transmembrane domain, and an intracellular signaling domain comprising at least a stimulatory domain, wherein prior to administering the cell, the subject is preconditioned with… The disclosure provides methods of treating a refractory or relapsed acute myeloid leukemia (AML) in a subject comprising administration of a cell comprising a nucleic acid molecule encoding a chimeric antigen receptor (CAR), wherein the CAR comprises an antibody or antigen-binding fragment thereof that binds IL-1RAP, a transmembrane domain, and an intracellular signaling domain comprising at least a stimulatory domain, wherein prior to administering the cell, the subject is preconditioned with a lymphodepleting chemotherapy (LDC)

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