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Metabolic Sources and Cellular Distribution of the NAD(H) and NADP(H) Couples NAD + , a key cofactor for many enzymes including metabolic enzymes, is critical for various biological processes (106)

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However, there is some evidence on the dysregulation of hypothalamic-pituitary axes caused by MPs and their composite EDCs (126, 127) like the HPT axis (138) and HPG axis (127) ( Table 8 )

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