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These include stress urinary incontinence after transabdominal urethrolysis and prolonged vaginal dilatation [116], glaucoma induction (episcleral veins cauterization) [73], esophagitis (tube insertion into sphincter(s)) [107,108,110], acute pancreatitis (bile duct ligation) [110], creation of fistulas [111,112,118], and, in particular, anastomosis creation [115]

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Likewise, the use of higher MW mPEG increases the particle size and slightly increases the NO release rate