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Chalcones exhibit a wide range of biological activities, including anti-inflammatory, antioxidant, antimicrobial, and anticancer effects, largely through the modulation of signaling pathways such as nuclear factor kappa B (NF-κB), phosphoinositide 3-kinase/protein kinase B (PI3K/Akt), and cyclooxygenase (COX) enzymes (Ugwu et al., 2016)
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Apr 25, 2026 The IOC's 5 Evidence-Backed Endurance Supplements (2026) The IOC's official list has just 5 evidence-backed supplements for endurance athletes: nitrate, creatine, caffeine, beta-alanine, sodium bicarbonate
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