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Mechanism of Action Lasix inhibits the Na⁺/K⁺/2Cl⁻ (NKCC2) co-transporter in the thick ascending limb, leading to: • Increased excretion of: • Sodium (Na⁺) • Potassium (K⁺) • Chloride (Cl⁻) • Water • Calcium and magnesium • Decreased blood volume and blood pressure ✅ 3
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