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Advantage: Sermorelin, based on longer clinical history and suitability for sustained therapy

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The fact that the smallpox vaccine is highly effective from the acute administration within seven days of likely exposure, among those that can safely take the vaccine and are assuredly within the 7 days, means that uninfected, or perhaps even the early-infected cell populations, can rapidly produce sufficient quantities of IL-12, IL-18, IFNy, and factors to stimulate NK cells, and Variola-specific CTL's to overcome the viral evasion proteins and stop the infection in this early phase