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Drugs most affected include immunosuppressants (cyclosporine, tacrolimus), certain chemotherapy agents, and medications with narrow therapeutic windows
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237 detected metabolic responses related to perturbations in glutamine metabolism in 47 independent breast cancer-derived cell lines, meaning that the inhibition of xCT promotes an adjustment in glutamine metabolism, which indirectly contributes to the import of cysteine through the exchange with glutamine-derived glutamate through xCT
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