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In turn, molecular oxygen can accept electrons from many of the electron carriers in the PET chain (Foyer and Hanke, 2022), a process that is called the ‘Mehler reaction’, or ‘pseudocyclic electron flow’

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In late perimenopause stages, when symptoms are often more severe, estrogen levels tend to wane more consistently, especially during anovulatory cycles, leading to sustained low estrogen levels post-menopause and the emergence of classic menopausal symptoms [13,75,76]