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Human Glutathione S-Transferase pi 1/GSTP1 ELISA Kit (Colorimetric) (NBP3-25939) by Novus, Part of Bio-Techne
By taking advantage of the potent catalytic activity of TYR that is mechanistically validated by ab initio molecular dynamics (AIMD) theoretical calculation and experimental catalysis performance, we develop a TYR-catalyzed in-situ formed proteolysis-targeting chimeras (PROTACs) to degrade intracellular TYR protein to decrease melanin synthesis for treating hyperpigmentation and a TYR-catalyzed in-situ activated prodrug strategy to overcome drug resistance for melanoma therapy
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[DOI] [PMC free article] [PubMed] [Google Scholar] 150.Pang Y., Zhang Y., Huang L., Xu L., Wang K., Wang D., Guan L., Zhang Y., Yu F., Chen Z., et al
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