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In this perspective, we tested the efficacy of DCA on 3D culture obtained from PANC-1 and BXPC-3 and showed that DCA treatment compromised the structure and viability of already formed spheroids and compromised spheroid formation from both cell lines
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There are now associations between protein S -glutathionylation and ER stress in human diseases such as ischemia/cardiovascular disease and Friedreich’s ataxia, Alzheimers disease, type 2 diabetes, cystic fibrosis, cataracts and sickle cell anemia (for discussion see [35])
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