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Increased expression of glutamine transporter SNAT2/SLC38A2 promotes glutamine dependence and oxidative stress resistance, and is associated with worse prognosis in triple-negative breast cancer

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Glutamic acid residue located at position 133 (Glu133) and Lysine at position 136 (Lys136), two electrostatic loop residues, are very crucial for guiding the oncoming O 2 − anion’s long-range approach