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To investigate the relationship between this association and the occurrence of the disease, studies should be conducted in men with prostate cancer with an established GSTM1 genotype and increased mercury exposure
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In this context, inflammatory cytokines and immune cell secretions function as a “regulatory valve.” In addition to NF-KB and Nrf2/HO-1, the NLRP3 inflammasome and cGAS-STING pathways also play distinctive roles in ferroptosis–inflammation crosstalk
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