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Frontiers | Glycolysis and glycolytic enzymes in acute myeloid leukemia: Warburg and beyond

Although glucose is a vital metabolite, and the main fuel for a large number of cells in the body, cells of the immune system, such as lymphocytes, neutrophils, and macrophages, utilize glutamine at high rates similar to or greater than glucose under catabolic conditions, such as sepsis, recovery from burns or surgery, and malnutrition, as well as high intensity/volume physical exercise [5,6]

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In addition to the intensive propidium iodide fluorescence of root cell nuclei indicating cell death in AITC-treated roots (Fig