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The small enhancement of AAT catalytic activity by light (up to ~4-fold increase in k cat at high power) is primarily due to the fact that deprotonation of the external aldimine intermediate is only partially rate limiting for k cat .[46] Subsequent light-insenstive steps in the L-Asp half-reaction (ketimine hydrolysis and product dissociation) are partially rate-limiting as is the second half-reaction

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GDIL binds to XRN2 and induces its cytoplasmic translocation Mature mRNAs are exported from nucleus to cytoplasm where they are transcribed, spliced, capped and polyadenylated