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Eupatilin protects against isotretinoin induced hepatotoxicity through immunomodulation of TLR4/MyD88/TRAF6 and NF-κB/NrF2 pathways - ScienceDirect
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Furthermore, specific TP53 mutants (e.g., R273H) disrupt AA and fatty acid (FA) metabolism and prevent cytoplasmic degradation of GAPDH, increasing cellular sensitivity to glycolysis inhibitors such as 2-deoxyglucose (2-DG) [160, 172]
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