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On the other hand, H 2 S produced in cytosol enhances the activity of cystine/glutamate antiporter to increase the transport of cystine, which is reduced to cysteine and used to produce GSH in cells 9
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IFNγ also induces an increase in barrier permeability through the reduction of ZO-1 and occludin expression in an adenosine monophosphate-activated protein kinase (AMPK)-dependent pathway, irrespective of the cellular energy levels 62
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