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In a clinical trial, patients with esophagitis (RE) were randomized into a test or control group, the test group received rabeprazole tablets + Streptococcus lactis MH-02, and the treatment group received rabeprazole tablets + placebo, and the results of the trial showed that patients in the test group experienced earlier symptom relief, significantly lower Gastrointestinal Symptom Rating Scale (GSRS) scores, and a longer mean time to relapse ( This paper will summarize the structural characteristics of the esophageal and intestinal microbiome of GERD and the known possible triggering mechanisms and potential future triggers are detailed

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