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glutathione peroxidase 1 mechanism Peroxidases: An Emerging and Promising Therapeutic Target for Pancreatic Cancer Treatment The role of di-(2-ethylhexyl)
The role of di-(2-ethylhexyl) phthalate in cancer initiation and progression: Mechanisms and health implications - ScienceDirect
T2DM develops due to insulin’s inhibitory effect on liver glucose production or due to different defects in insulin secretion
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Notably, breast cancer cells achieve metabolic adaptation by hijacking the autophagy mechanism: under glucose-deprivation conditions, MANF-mediated mitophagy eliminates dysfunctional mitochondria through the PRKN/Parkin-dependent pathway, maintains the ATP supply and promotes tumour survival [112], suggesting that targeting the MANF‒PRKN interaction can break the drug resistance barrier of breast cancer under metabolic stress
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