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NADPH has a dual function in redox regulation: it provides reducing equivalents for the redoxins, that is, the thioredoxin and glutaredoxin systems, as well as for glutathione disulfide reductase, whereas it generates oxidants by reducing molecular oxygen to superoxide in a reaction catalysed by NADPH oxidases (NOX)
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[DOI] [PMC free article] [PubMed] [Google Scholar] 269.Melrose J
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