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Successful desensitization can lead to a significant reduction or complete resolution of symptoms, including skin rashes, itching, and other allergic responses to progesterone
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Broad antagonism risks serious side effects due to the receptors’ involvement in many physiological processes, but subtype-specific modulation can reduce such risks—for instance, selective mAChR antagonists mitigate cardiovascular and nervous system side effects, while selective nAChR antagonists avoid impairing cognitive function
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