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It is primarily produced by skeletal muscle cells and acts as a brake on muscle growth through two mechanisms: Inhibition of satellite cell proliferation — myostatin suppresses the activation and proliferation of muscle stem cells (satellite cells) that are necessary for muscle hypertrophy and repair Suppression of protein synthesis — myostatin activates the Smad2/3 signaling pathway, which inhibits the mTOR pathway responsible for muscle protein synthesis Natural Myostatin Deficiency# The dramatic effects of myostatin loss were first demonstrated in Belgian Blue cattle — a breed with a natural myostatin gene mutation that produces extreme muscular hypertrophy (double muscling)

Indicaties>>Darmen & Darmflora

Measurement:2.5 kg

Autophagy as a therapeutic target in pancreatic cancer