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Removal of agonists or binding of antagonists in in-vitro conditions allows the receptor transition to resting/closed state by rearranging LBD to a dimeric state, which leads to re-positioning of the linkers between LBD and TM 31
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What it does in the MicroInfuser context: stimulates new collagen and elastin synthesis, activates lysyl oxidase for matrix crosslinking, modulates gene expression toward regenerative pathways, and replenishes the age-depleted dermal signaling pool
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