mucosal melanotic lesions Pigmented macule on the mandibular gingiva (a, case 1), affecting the Navigating pigmented oral lesions

Navigating pigmented oral lesions requires careful assessment. A blue-gray macule near a restoration, stable over time, and presenting with radiopaque particles suggests an amalgam tattoo. Conversely, an irregular, variegated, and rapidly growing

A 2022 meta-analysis combined 5 studies on corticosteroids (like prednisone) and found no difference in live birth rate

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Specifically, SIRT1 deacetylates autophagy-related proteins, such as Atg5, Atg7, and LC3, thereby facilitating autophagosome formation and enhancing lipophagy — the selective degradation of lipid droplets that reduces triglyceride accumulation (Lee et al