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Interestingly, chemogenetic or optogenetic inhibition of the glutamatergic neurons in the ACC, or exogenous administration of GABA, has been found to abolish paclitaxel-induced neuronal hyperexcitability and mechanical allodynia (Nashawi et al., 2016
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For instance, glutamine dose-dependently enhanced cell proliferation and differentiation of neonatal porcine and rat IECs, through activating multiple mitogen-activated protein kinases (MAPKs) (108–110)
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