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If the colonic bacterial community reaches a high cell density, quorum-sensing systems can facilitate cell-to-cell communication within the bacterial population by producing molecules such as CSF (sporulation-stimulating factor) and LSP (lipopolysaccharide

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Here we studied the presence of GLOS in the WAKE-UP trial and its association with HARM, hemorrhagic transformation (HT) and poor functional outcome (modified Rankin scale 3-6)