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Pathophysiological Mechanism of Oxidative Stress in Diabetes Prolonged oxidative stress promotes the development of diabetes and its complications by impairing the insulin secretion of beta cells, raising insulin resistance, sustaining hyperglycemic memory, and inducing systemic inflammation

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It leads to maternal adaptations that help meet the increased metabolic demands of pregnancy ( Prolactinoma While there are many causes of elevated prolactin levels, prolactinomas are the leading cause of hyperprolactinemia ( Table 1 ) ( Table 1 Causes of Hyperprolactinemia